spoiler
There shouldn't be any issues at that point then! Hopefully mono-therapy works for you.
some sex stuff
I'm less attracted to the physicality of sex all together, and I'm feeling more explicitly demisexual
Slightly off-topic, but I relate to this experience a lot. Before transition, I had always thought I was demisexual, but I did not feel like it at all. It made me feel a little miserable, like my mind wanted one thing and my body another. Now, I would definitely say I'm demisexual, and potentially asexual as well, and it feels more like mind and body are in sync. Speaking of which...
This actually reminded me of something. HRT could impact libido, especially if you were to take a T blocker like Spiro or CPA (Bica circumvents the libido issue). I would say more than that, but any other thoughts I have are just semi-theoretical personal experiences. I'm sure there are other people here who would have more to say on this topic, and are more knowledgeable than I.
spoiler
I don't think it will actually shift anything. It's more like it highlights things that people may not have realized were there before. For me, I've always known that I've wanted a feminine presence in a relationship. This naturally meant I was straight, and I assumed I would exclusively be a lesbian after transition. However, I've realized that I could play the role of the feminine presence, that is now me, so while I would say that I like masculinity now as well, that doesn't mean my love for femininity and androgyny have gone away. Being able to change what role I play in a relationship has changed how I see relationships, and even then, this is all theory. I have no praxis to speak of, I don't know how well ANY of these claims would hold up in a real relationship, because honestly I could be ace (more likely) or aroace (less likely) and just want some close friends (which I've never really had), I have literally no clue, and I haven't gotten to put my thoughts into praxis yet.
If you are attracted to your wife, you will still be attracted to your wife, especially if you are satisfied with the relationship. If you realize you might like other people as well, that may have already been there, but I don't think it would change how you see your wife. Don't let this stop you from trying E, and if it was doing things you didn't like, you could always just stop it. Also, I don't know if it was the E that necessarily did it, but me beginning to realize dynamics between the masculinity of others and the femininity of myself. Just adding that in there, because I feel like what happened with me would have happened with or without HRT.
Hold on, checking again...
It's not ready yet (it's a lab) 
Hey this feminist ethical theorist is taking a pretty marxist view on feminism, I wonder what the rest of the class is going to say about the issues that still face us today!
On the HRTersary, congrats!
On everything else, 
OOH, as of right now, my week covers His birthday 
Doing my injection and now constantly wondering what my levels are as I sit in anticipation.
Once it was done, I went to check the webpage that shows the results, spamming ctrl-shift-r. STOP DOING THAT AshenWolf/Ashen/Ash/Wolf/Wolfie/Luna/Luna'sAlt, THE RESULTS AREN'T GOING TO BE POSTED YET 
Also, 
and now its kind of a whole pendulum/dual thing for me
