this post was submitted on 22 Dec 2023
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[–] OhNoMoreLemmy@lemmy.ml 5 points 11 months ago (1 children)

I was listening to a sleep scientist the other day and they were saying that one thing we know is that depressed people have more rem sleep on average, and SSRIs decrease the amount of rem sleep.

If it is something sleep based that goes some way to explaining why it takes time to have an effect. Building up or wiping out a sleep debt can't happen instantaneously.

[–] GuyDudeman@lemmy.world 4 points 11 months ago (1 children)

That’s interesting… because I always thought that REM sleep was the most important part of sleep, and more was better.

In fact, I read an article once that suggested that REM sleep was when our spinal fluid flushed all the waste material out of our brains at night (which leads to the types of dream that occur during REM sleep), which is also a process that prevents brains from being clogged with waste material.

I always thought that our brains being filled with waste material was part of depression, and that flushing out that waste material would help our brains function more correctly.

Sounds like the opposite - like, our depressed brains are depressed because they think too much?

[–] OhNoMoreLemmy@lemmy.ml 2 points 11 months ago

Characteristic sleep-EEG changes in patients with depression include disinhibition of rapid eye movement (REM) sleep, changes of sleep continuity, and impaired non-REM sleep.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386825/

Yeah, I think we have multiple types of sleep because we need them, and if you're getting too much rem sleep at the expense of other types it's going to cause problems.