this post was submitted on 05 Dec 2023
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Vaccines can be delivered through the skin using ultrasound. This method doesn’t damage the skin and eliminates the need for painful needles. To create a needle-free vaccine, Darcy Dunn-Lawless at the University of Oxford and his colleagues mixed vaccine molecules with tiny, cup-shaped proteins. They then applied liquid mixture to the skin of mice and exposed it to ultrasound – like that used for sonograms – for about a minute and a half.

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[–] deranger@lemmy.world 2 points 11 months ago* (last edited 11 months ago) (3 children)

What do you think about jet injectors?

a narrow, high-pressure stream of liquid penetrates the outermost layer of the skin to deliver medication to targeted underlying tissues

https://en.wikipedia.org/wiki/Jet_injector

[–] takeda@lemmy.world 3 points 11 months ago (1 children)

This is what I was thinking when reading the title. That one supposedly was cool, because there was no needle, never seen one in action but I presume there also was no bleeding.

Yet we don't see them used today, apparently the biggest reason was that there was a splashback and retrograde follow and then patient's blood could end up contaminating the nozzle, so basically it was like using the same needle on multiple patients.

[–] buddhabound@lemmy.world 5 points 11 months ago (2 children)

They're not cool. They're fast and good for giving lots of shots in a situation where you need to get a lot of people in a hurry - especially if you're giving multiple vaccinations at the same time.

I got one of those used on me in basic training - a place where you need to vaccinate a few thousand people in about 30 minutes. Each one could do 4 shots at a time, and they had them in multiple configurations so you could get up to 4 in each arm for each "injection" station. We stepped through the line, and you got whatever shots you were missing in your records.

It hurts, like you could imagine a high pressure power washer with a needle-point burst with 4 heads blasting vaccines in your arms. It works, in the machine-like way the military works, and it is highly effective for mass vaccinations. So, I guess it makes it cool, but also it sucks like you'd expect 4-30 vaccines at once would suck.

[–] Alto@kbin.social 5 points 11 months ago* (last edited 11 months ago) (1 children)

Grandpa told me about a guy in basic that jerked when they shot it, absolutely tore open his arm.

Fuck that, give me the needle. And I fucking hate needles.

[–] Maeve@kbin.social 0 points 11 months ago

I’m right there with you.

[–] reflex@kbin.social 1 points 11 months ago* (last edited 11 months ago)

What do you think about jet injectors?

That one supposedly was cool

They’re not cool.

What a wild ride. 😏

[–] Neato@kbin.social 2 points 11 months ago

It's how I got some vaccines in gradeschool. To the underside of my upper arm, the fatty bit. Hurt like fuck.

[–] Maeve@kbin.social 0 points 11 months ago

I think no. I don’t like needles either, but I’ll deal with those first.