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While CHS is the likely culprit, it could also be an allergy that's built up over time. Most people don't realize it's possible to be allergic to cannabis, but it is indeed. Source: I'm allergic to cannabis.
If so, look into desensitization methods. Not sure if they work with an acquired allergy or not though.
Just commenting to second the allergy, even tho it may not be the issue here. I always had awful reactions over the ~15 years I tried it off and on. Terrible. Not like CHS at all. You're right, allergy (or something) is a thing. But probably not what OP has (not a doctor).
Yeah, I'm pretty sure it's not CHS. From what I've read, CHS is similar to overdosing, and is mostly associated with habitual users. The very first time I got stoned, decades ago, I spent the entire night in my car parked outside of a friend's house trying to not be violently ill. Since then, after legalization, I've gotten mildly stoned on edibles a couple of times to no ill effect, but the third time the nausea was back.
I've found no reference about it online. I've asked about it, online. I don't know of it's allergies in my case; if I mini-dose - amounts small enough that I can't notice any effect, but more than homeopathic doses - I'm fine. But as soon as I take enough to geta even a mild high, bang: nausea.
It's really frustrating, because I suffer from chronic lower back pain (thanks, Army!) and I'd even gotten a prescription (before it was recreationally legal in my state) in an attempt to achieve the pain relief associated with cannabis.
I've now chalked it up to a paradoxical effect. I suspect the anti-nause mechanism in THC is behaving differently in my biome and instead triggers nausea. Maybe that can be classified as an allergy? Although I expect if it were a traditional allergy, any amount would trigger nausea. And a little cannabis doesn't make me a little sick; it's either all or nothing.
My other theory is that it's zero-G sickness. When I get high, I get a head-spinning effect, and that sort of thing over a long term induces nausea in me.
I don't know what the fuck it is, but it's gods-damned annoying.
This might be silly to ask, but have you tried high CBD strains instead of "purely recreational" ones (which often have high THC and abysmally low CBD)?
CBD attenuates some effecs of THC. I very much doubt it would change the behaviour of THC completely for you, but there's still a lot we need to learn about cannabis so, I wouldn't say anything for certain.
That's a good idea. I can't say I've prayed much attention to the CBD content. Maybe I'll give that a try, although being nauseous for four hours is almost not worth experimenting with.