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What is a hobby you enjoy, but seems too quirky or obscure to bring up in most conversations? (lemmy.sdf.org)

submitted 1 year ago by Rozz@lemmy.sdf.org to c/asklemmy@lemmy.ml

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Mine would be creating pen and paper ciphers for my made up secret communication needs.

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[–] Rozz@lemmy.sdf.org 1 points 1 year ago (1 children)

That's pretty cool. A unique type of puzzle to solve

[–] xkforce@lemmy.world 1 points 1 year ago* (last edited 1 year ago)

A puzzle is a pretty good analogy for designing drug molecules. Drugs interact with proteins and enzymes much like trying to snap a puzzle piece into a puzzle. i.e lock and key model. Currently the strategy drug companies use essentially amounts to synthesizing millions of potential drug candidates in small quantities and testing for target activity. This is... horribly inefficient and it is hoped that better modeling can help cut down on either the number of candidate drugs that need to be screened and/or refine the drugs' activity to be more targeted (reduce side effects)