The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
I mean, being a minority, I can't help but see that as a distinction without a difference; the right-wing, if not outright fascist, is definitely flirting with it and that already makes me want to distance myself