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Genetic variants linked to ADHD and Parkinson's, Queensland led study on brain size finds (www.abc.net.au)

submitted 1 month ago by Deceptichum@quokk.au to c/world@quokk.au

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"Larger brain volumes tend to increase the risk of Parkinson’s disease later in life and smaller brain volumes tend to increase the risk of ADHD."

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[–] Apytele@sh.itjust.works 7 points 1 month ago (1 children)

Makes sense, actually; dopamine is highly implicated in both disorders. ADHD responds to stimulants because they increase dopamine. Unfortunately they can also cause psychosis in large enough doses (common problem with meth and cocaine use). Antipsychotics, which reverse the psychosis... cause pseudoparkinsonianism, or drug-induced Parkinsons. Not sure exactly how this part of the puzzle fits in, but I've definitely seen some other puzzle pieces from that corner, to extend the metaphor.

[–] Pronell@lemmy.world 1 points 1 month ago* (last edited 1 month ago) (1 children)

Yup, I think tardive diskenesia is the same thing. If you've seen old videos from asylums where the patients are twitching rather violently, that's advanced tardive diskenesia.

More modern medicines don't cause it to be as pronounced but it's still an issue.

[–] Apytele@sh.itjust.works 2 points 1 month ago

I've actually both had it and treated my patients for it!